Levit IV Patient Counseling Information

Suicidal Behavior and Ideation: Counsel patients, their caregivers, and/or families that antiepileptic drugs (AEDs), including Levetiracetam, may increase the risk of suicidal thoughts and behavior and advise patients to be alert for the emergence or worsening of symptoms of depression; unusual changes in mood or behavior; or suicidal thoughts, behavior, or thoughts about self-harm. Advise patients, their caregivers, and/or families to immediately report behaviors of concern to a healthcare provider.
Psychiatric Reactions and Changes in Behavior: Advise patients and their caregivers that Levetiracetam may cause changes in behavior (e.g., aggression, agitation, anger, anxiety, apathy, depression, hostility, and irritability) and psychotic symptoms.
Effects on Driving or Operating Machinery: Inform patients that Levetiracetam may cause dizziness and somnolence. Inform patients not to drive or operate machinery until they have gained sufficient experience on Levetiracetam to gauge whether it adversely affects their ability to drive or operate machinery.
Dermatological Adverse Reactions: Advise patients that serious dermatological adverse reactions have occurred in patients treated with Levetiracetam and instruct them to call their physician immediately if a rash develops.
Pregnancy: Advise patients to notify their healthcare provider if they become pregnant or intend to become pregnant during Levetiracetam therapy. Encourage patients to enroll in the North American Antiepileptic Drug (NAAED) pregnancy registry if they become pregnant. This registry is collecting information about the safety of antiepileptic drugs during pregnancy. [see Pregnancy & Lactation].