Lenalid 5/Lenalid 10/Lenalid 15/Lenalid 25 Special Precautions

Before administration of Lenalidomide (Lenalid) capsules be advised if patients: are pregnant or are planning to get pregnant; are breastfeeding; have kidney problems; have liver problems; have blood problems; have or have had heart problems (irregular heart beat, heart attack); smoke, have high blood pressure or high cholesterol levels; have had previous viral infection including herpes zoster infection (shingles) and/or hepatitis B virus infection (a viral infection of the liver); have had organ transplantation.
Lenalidomide (Lenalid) capsules may cause birth defects. In order to take this drug patient must meet the following conditions: Females who can get pregnant: Discuss contraception (birth control) with the healthcare provider.
Use at least two effective methods of contraception at the same time.
Use these two effective methods of contraception: For at least 4 weeks before starting Lenalidomide (Lenalid) capsules treatment; During interruptions of Lenalidomide (Lenalid) capsules treatment; During Lenalidomide (Lenalid) capsules treatment; For at least 4 weeks after stopping Lenalidomide (Lenalid) capsules treatment.
Patient must have two negative pregnancy tests before starting treatment: The first 7-14 days prior to starting treatment; The second within 24 hours of starting treatment.
Patient must have negative pregnancy tests during treatment: Once weekly for the first 4 weeks; Once every 4 weeks (or once every 2 weeks if patient period is irregular) for the duration of treatment and during treatment interruption.
Patient must have a final pregnancy test 4 weeks after stopping Lenalidomide (Lenalid) capsules.
Males: Lenalidomide is present in the sperm of males who take this drug. Should use a condom every time they have sexual intercourse with a woman who is pregnant or can get pregnant. This must be done even if they have undergone a successful vasectomy. The condom must be used while: Patient is taking Lenalidomide (Lenalid) capsules; During interruptions of treatment; For 4 weeks after stopping Lenalidomide (Lenalid) capsules.
They should not donate sperm while taking Lenalidomide (Lenalid) capsules and for 4 weeks after stopping Lenalidomide (Lenalid) capsules.
Patient should inform their sexual partner who can get pregnant that: They are taking Lenalidomide (Lenalid) capsules; There is a risk of birth defects, stillbirths, and spontaneous abortions if a fetus is exposed to their sperm; Patient must use a condom.
The patient should contact their doctor immediately if they think that their female partner becomes pregnant while they are taking Lenalidomide (Lenalid) capsules.
All Patients: Lenalidomide (Lenalid) capsules may cause birth defects and any method of birth control can fail. They should contact their doctor immediately if they think they or their female partner may be pregnant. They should also contact their doctor if they miss their period or experience unusual menstrual bleeding.
Patient should not give blood while they are taking Lenalidomide (Lenalid) capsules and for 4 weeks after stopping Lenalidomide (Lenalid) capsules.
Patient should not share Lenalidomide (Lenalid) capsules with other people.
Lenalidomide (Lenalid) capsules is not recommended for use in children under 18 years of age.
Lenalid 5/Lenalid 10: Myelodysplastic syndromes: Second cancers such as skin cancers, blood cancers, and solid tumor cancers have been reported in a small number of patients while taking lenalidomide or after treatment with lenalidomide is completed. Patients should talk to their doctors if they have any concerns about their own increased risk of having other cancers.