Khriz-Ors

Each sachet (20.5 g) contains: Sodium Chloride 2.6 g, Potassium Chloride 1.5 g, Sodium Citrate 2.9 g, Anhydrous Glucose 13.5 g.
Each 1 L contains: Citrate 10 mmol, Potassium 20 mmol, Chloride 65 mmol, Sodium 75 mmol, Glucose 75 mmol.
This medicine contains Glucose and various salts which belong to a group of medicines called oral electrolytes which act to replace lost fluids and salts. It can be used to relieve short term (acute) diarrhea and replace lost salts and fluids, in order to prevent dehydration.

Electrolyte replenisher.

This medicine is used to replace ions and salts that the body loses due to dehydration caused by diarrhea. Excessive sweating, severe diarrhea or vomiting makes the patient lose more fluids, and thus also salts and sugars, than they usually would and can make them dehydrated. Dehydration is characterized by increased thirst, dry eyes and mouth, drowsiness, less or no urination, confusion, and in severe cases, fainting. Infants, small children, pregnant women and frail or elderly people are more prone to dehydration when there is excessive loss of fluid. ORS prevents dehydration. The sugars and salts in the sachets help the water to be absorbed from the intestines and restore moisture balance in the body.

As per WHO manual for the treatment of Diarrhea provides the following information on the assessment and treatment of dehydration: How to assess the degree of dehydration and choose a treatment plan: See Table 1.

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How Much ORS Solution to be Used Based on Patient Assessment and Treatment Plan: Check the sachet if not broken before use. If it is, do not take the sachet.
Daily dose should be equivalent to patient's fluid requirement for maintenance and replacement of loses.
Prevention of dehydration (WHO - Treatment plan A): Direction: The contents of one sachet should be dissolved in sufficient clean drinking water to make 250 mL. However, the solution may be used for up to 24 hours if stored in a refrigerator immediately after reconstitution. The reconstituted solution must not be boiled.
Give as much fluid as the child or adult wants until diarrhea or vomiting stops or they may use the following guide according to the WHO: Child under 24 months: 50 to 100 mL after each loose stool (approximately 500 mL daily).
Child from 2 to 10 years: 100 to 200 mL after each loose stool (approximately 1000 mL daily).
Child over 10 years and adults: 200 to 400 mL after each loose stool (approximately 2000 mL daily).
Treatment of moderate dehydration (WHO - Treatment plan B): Direction: The contents of one sachet should be dissolved in sufficient clean drinking water to make 250 mL. However, the solution may be used for up to 24 hours if stored in a refrigerator immediately after reconstitution. The reconstituted solution must not be boiled.
Child and Adult: Over the first four hours: See Table 2.

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After four hours: If there are no signs of dehydration: follow Treatment plan A.
If there are signs of moderate dehydration: repeat Treatment plan B.
If there are signs of severe dehydration: start IV therapy (Treatment plan C).
Treatment of severe dehydration (WHO - Treatment plan C): In combination with IV therapy and only to a conscious patient: Child and adult: 5 mL/kg per hour.
After 3 hours (6 hours in infants), reassess and choose the appropriate plan A, B or C.
Continue treatment until diarrhea stops/dehydration is corrected.
What Should the Patient Do if they Miss a Dose: Do not take a double dose to make up for a forgotten dose. If the patient forgets to take a dose, take it as soon as they remember it and then take the next dose at the right time. If the patient has any further questions on the use of this medicine, ask the doctor or pharmacist.

There is no information regarding overdosage. Do not use more than prescribed dose.
When the Patient Has Taken More than the Recommended Dose: If the patient has taken more than the recommended dosage than they should, seek immediate medical advice even if they feel well.
Reporting of Overdosage: If the patient (or someone else) accidentally takes more than recommended dosage at the same time, contact the nearest hospital casualty department or tell a doctor immediately or a Poison Control Center right away. Show any leftover medicines or the empty packet to the doctor.

If the patient is allergic to any component of the product or if they have glucose malabsorption.

Follow direction for use and recommended dose to avoid overdosing. See previous tables.
ORS may be used in severe dehydration only if intravenous fluid is not available. Don't use more than recommended dose. The solution may be used for up to 24 hours if stored in a refrigerator immediately after reconstitution. The reconstituted solution must not be boiled.

There are no undesirable effects if the recommended dilution, volume of ORS solution to be administered and dosing are followed. If the patient notices any side effects talk to the pharmacist or doctor.
Reporting of Side Effects: If the patient gets any side effects, talk to a doctor or pharmacist. This includes any possible side effects not listed in this monograph.

This medicine is not expected to affect any other medicines that the patient may be taking. If the patient is unsure about interactions with any medicines, talk to a pharmacist. This includes medicines prescribed by a doctor and medicine the patient has bought for themselves, including herbal and homeopathic remedies.

Store at temperatures not exceeding 30°C.
Do not use this medicine after the expiry date which is stated on the label/carton/bottle. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask the pharmacist how to throw away medicines the patient no longer requires. These measures will help protect the environment.

Electrolytes

A07CA - Oral rehydration salt formulations ; Used in the treatment of diarrhea.