The simultaneous administration of medications containing calcium (eg, acetolyte) may lead to pathological increases of the serum calcium level or intensification. As the uremia symptoms improve with Ketosteril, a possible administration of aluminium hydroxide should be reduced. Pay attention to a reduction of serum phosphate. In order not to interfere with absorption, do not take drugs together with Ketosteril that form sparingly soluble compounds with calcium (eg, tetracyclines).