Ketesse Contraindications

Absolute Contraindications: Not to be given to those patients who have history of: Stroke: cerebrovascular accident, CVA.
Heart attack: Myocardial infarction, MI.
Coronary artery bypass graft: CABG.
Uncontrolled hypertension.
Congestive heart failure (CHF) NYHA II-IV.
Ketesse FC tab: Dexketoprofen (KETESSE) tablets must not be administered in the following cases: patients hypersensitive to Dexketoprofen, to any other NSAID, or to any of the excipients of the product; patients in whom substances with a similar action (e.g. aspirin, or other NSAIDs) precipitate attacks of asthma, bronchospasm, acute rhinitis, or cause nasal polyps, urticaria or angioneurotic edema; patients with active or suspected peptic ulcer/haemorrhage or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding) or chronic dyspepsia; patients with history of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy; patients who have gastrointestinal bleeding or other active bleedings or bleeding disorders; patients with Crohn's disease or ulcerative colitis; patients with a history of bronchial asthma; patients with severe heart failure; patients with moderate to severe renal dysfunction; patients with severely impaired hepatic function; patients with haemorrhagic diathesis and other coagulation disorders; during the third trimester of pregnancy and the lactation period.
Ketesse Solution for Injection or Concentrate for Solution for Infusion (I.V/I.M.): Dexketoprofen (KETESSE) Solution for Injection or concentrate for solution for infusion must not be administered in the following cases: patients hypersensitive to Dexketoprofen, to any other NSAID, or to any of the excipients of this medicinal product; patients in whom substances with a similar action (e.g. acetylsalicylic acid and other NSAIDs) precipitate attacks of asthma, bronchospasm, acute rhinitis, or cause nasal polyps, urticaria or angioneurotic edema; patients with active or suspected peptic ulcer/haemorrhage or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding); patients who have gastrointestinal bleeding or other active bleedings or bleeding disorders; patients with history of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy; patients with Crohn's disease or ulcerative colitis; patients with a history of bronchial asthma; patients with severe heart failure; patients with moderate to severe renal dysfunction (creatinine clearance <50 mL/min); patients with severely impaired hepatic function (Child-Pugh score 10-15); patients with haemorrhagic diathesis and other coagulation disorders; during the third trimester of pregnancy and the lactation period.
Decketoprofen (KETESSE) Solution for Injection or concentrate for solution for infusion is contraindicated for neuraxial (intrathecal or epidural) administration due to its ethanol content.