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Tablet: Furosemide is a potent diuretic with a rapid action. Like the other loop or high-ceiling diuretics, it is used in the treatment of oedema associated with heart failure, including pulmonary oedema and with renal and hepatic disorders and may be effective in patients unresponsive to thiazide diuretics. It is also used in high doses in the management of oliguria due to renal failure or insufficiency. Furosemide is also used in the treatment of hypertension either alone or together with other antihypertensives.
Furosemide inhibits the reabsorption of electrolytes primarily in the thick ascending limb of the loop of Henle and also in the distal renal tubules. Excretion of sodium, potassium, calcium and chloride ions is increased and water excretion enhanced. It has no clinical significant effect on carbonic anhydrase.
Injection: For the treatment of oedema associated with heart failure, pulmonary oedema, and with renal & hepatic disorders. For patients unresponsive to thiazide diuretics and management of oliguria due to renal failure or insufficiency & for hypertension.
