Kenaxef Adverse Reactions

Shock: As shock may rarely occur, cautious monitoring is required, and in case that unpleasantness, stridor, dizziness, tenesmus, tinnitus, perspiration, etc., occur, further administration should be discontinued and appropriate measure should be taken.
Hypersensitivity: In case of exanthema, urticaria, erythema, flaire, pruritis, shivering, fever, allergic dermatitis, edema, erythema multiforme, anaphylactic or anaphylactic like reaction occur, further administration should be discontinued and appropriate measure should be taken.
Blood: Occasionally granulocytopenia, eosinophilia, thrombocytosis, leukopenia, rarely anemia, hemolytic anemia, thrombocytopenia, prothrombin abnormality may occur.
Liver: Occasionally elevation of GOT, AL-P and symptomatic precipitation of ceftriaxone calcium salt in gall bladder rarely elevation of bilirubin, γ-GTP may occur.
Kidney: As severe renal disorder such as acute renal insufficiency is reported rarely, caution monitoring is required and if abnormality is acknowledged further administration should be discontinued and appropriate measures should be taken.
GI System: Rarely severe enterocolitis with hemafecia such as pseudomembranous enterocolitis may occur. If abdominal pain and frequent diarrhea occur, appropriate measures such as immediate discontinuation of Ceftriaxone should be taken. Also occasionally nausea, vomiting, loose stools, diarrhea or rarely abdominal pain, anorexia, etc. should be taken.
Respiratory System: In the administration of other cephem series antibiotics, interstitial pneumonia accompanying with flush, cough, dyspnea, disorder of chest X-ray, eosinophilia, and PIE syndrome may occur rarely. If those symptoms occur the administration should be discontinued and/or appropriate therapy including the administration of adrenocortical hormone should be instituted.
Superinfection: Rarely stomatitis, candidasis may occur.
Avitaminosis: Rarely, avitaminosis K (e.g. hypoprothrombinemia, bleeding tendency) and vitamin B deficiency (e.g. Glossitis, stomatitis, anorexia, neuritis, etc.) may occur.
Others: Occasionally headache and rarely dizziness, edema, precipitation in gallbladder, ventricular extrasystole, elevated creatinine of blood, genital mycosis may occur.