View Janclav overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Best taken at the start of meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity to co-amoxiclav or to any of the penicillins. History of severe immediate hypersensitivity reaction (eg, anaphylaxis) to another β-lactam agent; jaundice/hepatic impairment due to amoxicillin/clavulanic acid.
Hypersensitivity (including anaphylactoid & severe cutaneous adverse reactions). Not to be used to treat penicillin-resistant S. pneumoniae. Convulsions may occur in patients w/ renal impairment or those receiving high doses. Increase allergic skin reactions in concomitant use of allopurinol. Prolonged use may occasionally result in overgrowth of non-susceptible organisms. Discontinue use in the occurrence of feverish generalized erythema associated w/ pustula. Hepatic events predominantly in males & elderly & may be associated w/ prolonged treatment. Antibiotic-associated colitis. Crystalluria has been observed in patients w/ reduced urine output. False +ve results may occur w/ non-enzymatic methods of testing for presence of glucose in urine; Coombs test; Bio-Rad laboratories Platelia Aspergillus EIA test. void use during pregnancy. Breast-feeding should be discontinued due to the possibility of sensitization.
Increased INR w/ acenocoumarol or warfarin. May reduce excretion of MTX causing a potential increase in toxicity. Decreased renal tubular secretion & may result in increased & prolonged blood levels of amoxicillin w/ probenecid. Reduced pre-dose conc of the active metabolite of mycophenolate mofetil.
J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
Sign Out
