Adult & elderly Individualized dosage. Max: 200 mg not >3 times/wk. IV drip infusion 5 mL (100 mg Fe) diluted soln in at least 15 min or 10 mL (200 mg Fe) in at least 30 min. Slow IV inj Rate: 1 mL (20 mg Fe) undiluted soln/min (ie, 5 min/amp) not exceeding 2 amp (200 mg Fe)/inj.
Hypersensitivity. Anemias not attributable to Fe deficiency. Fe overload or disturbances in utilisation of Fe. Patients w/ history of asthma, eczema or other atopic allergy. Pregnancy (1st trimester).
Periodic monitoring of hematologic & anti-anemia parameters (Hb, hematocrit, serum ferritin & transferrin saturation); w/held therapy in patients w/ evidence of Fe overload. Acute or chronic infection. Stop administration in patients w/ ongoing bacteremia. Hypotensive episodes if administered too rapidly. Allergic reactions, sometimes involving arthralgia. Avoid paravenous leakage. Avoid in patients w/ hepatic dysfunction where Fe overload is precipitating factor particularly porphyria cutanea tarda. Pregnancy & lactation. Not recommended in childn.
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