Invanz Description

Each vial contains 1.046 g ertapenem sodium, equivalent to 1 g ertapenem.
The sodium content is approximately 137 mg (approximately 6.0 mEq).
ERTAPENEM (INVANZ) is a sterile, synthetic, long-acting, parenteral, 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics, such as penicillins and cephalosporins, with activity against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria.
ERTAPENEM (INVANZ) is chemically described as [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-3-[[5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0] hept-2-ene-2-carboxylic acid monosodium salt.
Its empirical formula is C₂₂H₂₄N₃O₇SNa.
Ertapenem sodium is a white to off-white hygroscopic, weakly crystalline powder, with a molecular weight of 497.50. It is soluble in water and 0.9% sodium chloride solution, practically insoluble in ethanol, and insoluble in isopropyl acetate and tetrahydrofuran.
ERTAPENEM (INVANZ) is supplied as sterile lyophilized powder for intravenous infusion after reconstitution with appropriate diluent (see Instructions For Use under Dosage & Administration) and transfer to 50 mL 0.9% Sodium Chloride Injection or for intramuscular injection following reconstitution with 1% lidocaine hydrochloride.