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Non-steroidal anti-inflammatory drugs (NSAIDs) may antagonise the antihypertensive effect.
Concurrent use with sympathomimetics may reduce the antihypertensive effects.
Potassium-sparing diuretics: may lead to elevation of serum potassium.
Concurrent administration of sublingual nitroglycerin, long-acting nitrates, beta-blockers or other antianginal agents with amlodipine may produce additive antihypertensive and antianginal effects.
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