Humulin R Caution For Usage

Incompatibilities: Insulin Human (rDNA) (Humulin R) preparations should not be mixed with insulins produced by other manufacturers or with animal insulin preparations.
Special precautions for disposal and other handling: Do not reuse needles. Dispose of the needle in a responsible manner. Needles must not be shared. Vials can be used until empty, then properly discard. Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Instructions for use and handling: A solution for injection in a 10 mL vial to be used in conjunction with an appropriate syringe (100 IU/mL markings).
a) Preparing a dose: Vials containing Insulin Human (rDNA) (Humulin R) formulation do not require resuspension and should only be used if it is clear, colorless, with no solid particles visible and if it is of water-like appearance.
Mixing of insulins: The shorter acting insulin should be drawn into the syringe first, to prevent contamination of the vial by the longer acting preparation. It is advisable to inject directly after mixing. However, if a delay is necessary, a consistent routine must be followed.
Alternatively, a separate syringe or, separate cartridges of Insulin Human (rDNA) (Humulin R) and Insulin Human (rDNA) (Humulin N) can be used for administration of the correct amount of each formulation.
Prepare syringe prior to injection, as directed by the doctor or diabetes specialist nurse. Use an insulin syringe marked for the strength of insulin being administered.
b) Injecting a dose: Inject the correct dose of insulin, as directed by the doctor or diabetes specialist nurse. Use of the injection sites should be rotated so that the same is not used more than approximately once a month.