Long-term continuous topical therapy with fusidic acid + betamethasone valerate (Fucicort) should be avoided.
Depending on the application site, possible systemic absorption of betamethasone valerate should always be considered during treatment with fusidic acid + betamethasone valerate (Fucicort).
Due to the content of corticosteroid, fusidic acid + betamethasone valerate (Fucicort) should be used with care near the eyes. Avoid getting fusidic acid + betamethasone valerate (Fucicort) into the eyes (see Adverse Reactions).
Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression may occur following systemic absorption of topical corticosteroids.
Fusidic acid + betamethasone valerate (Fucicort) should be used with care in children as paediatric patients may demonstrate greater susceptibility to topical corticosteroids-induced HPA axis suppression and Cushing's syndrome than adult patients. Avoid large amounts, occlusion and prolonged treatment (see Adverse Reactions).
Due to the content of betamethasone valerate, prolonged topical use of Fusidic acid + Betamethasone valerate (Fucicort) may cause skin atrophy.
Bacterial resistance has been reported to occur with the topical use of fusidic acid. As with all antibiotics, extended or recurrent use of fusidic acid may increase the risk of developing antibiotic resistance. Limiting therapy with topical fusidic acid and betamethasone valerate to no more than 14 days at a time will minimise the risk of developing resistance.
This also prevents the risk that the immunosuppressive action of corticosteroid might mask any potential symptoms of infections due to antibiotic-resistant bacteria.
Due to the content of corticosteroid having immunosuppressant effect, fusidic acid + betamethasone valerate (Fucicort) may be associated with increased susceptibility to infection, aggravation of existing infection, and activation of latent infection. It is advised to switch to systemic treatment if infection cannot be controlled with topical treatment (see Contraindications).
Fusidic acid + betamethasone valerate (Fucicort) cream contains cetostearyl alcohol and chlorocresol as excipients. Cetostearyl alcohol may cause local skin reactions (e.g. contact dermatitis) and chlorocresol may cause allergic reactions.
Effects on the Ability to Drive and Use Machines: Fusidic acid + betamethasone valerate (Fucicort) has no or negligible influence on the ability to drive or to use machines.
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