Frusema Dosage/Direction for Use

For Edema: Adults: Initially 40 mg in the morning; maintenance of 20 mg to 40 mg daily, increased in resistance edema to 80 mg daily or more.
Children: Initially, 1 mg to 3 mg/kg daily, maximum of 40 mg daily.
20 mg tablet: Adult: 20 to 80 mg single dose daily preferably in the morning; dose may be titrated and given in divided doses every 6 to 8 hours.
Children: Start with 2 mg/kg/dose, if diuretic response is not achieved, increase dose by 1-2 mg/kg every 6-8 hours. After initial dose, maximum 6 mg/kg with an interval of at least 2 hours between doses. Or as prescribed by the physician.
For Oliguria in chronic renal impairment: Initially 250 mg daily; If necessary, larger doses, increasing in steps of 250 mg, maybe given every 4 to 6 hours to a maximum of 1.5 g in 24 hours may be given.
Or, as prescribed by the physician.
40 mg tablet: For hypertension: 40 to 80 mg daily, either alone or in conjunction with other antihypertensives.
For Oliguria in chronic renal impairment: An initial dose of 250 mg may be given, increase if necessary in steps of 250 mg every 4 to 6 hours to a maximum of 1.5 g in 24 hours.
Or as prescribed by the physician.