Mupirocin, betamethasone dipropionate.
Each gram contains: Mupirocin 20 mg, Betamethasone dipropionate500 mcg.
Pharmacology: Mechanism of Action: Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase. Due to this unique mode of action, Mupirocin demonstrates no in vitro cross-resistance with other classes of antimicrobial agents.
Topical corticosteroids, such as Betamethasone dipropionate, are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, anti-pruritic and vasoconstrictive actions.
For the treatment of corticosteroid-responsive dermatoses with secondary bacterial infection.
The recommended dosage is to apply the ointment to the affected area 3 times daily. Patients with severe infections may require a longer treatment period and if systemic involvement develops, systemic antibiotics may be necessary.
Or as prescribed by the physician.
Contraindicated in patients who are hypersensitive to any of its ingredients.
Avoid contact with eyes.
Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.
The treated skin area should not be bandaged or otherwise covered or wrapped as to be occlusive.
Polyethylene Glycol formulations of Mupirocin should not be applied to extensive open wounds.
Pregnancy: Pregnancy Category C.
Topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Nursing Mothers: Caution should be exercised when topical corticosteroids are prescribed for nursing women.
Generally well tolerated. Burning, stinging, skin atrophy, striae, dryness, acneiform eruptions, hypopigmentation. Systemic absorption of Betamethasone dipropionate can produce HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia and glycosuria in some patients.
Store at temperatures not exceeding 30°C.
Do not freeze.
D07CC01 - betamethasone and antibiotics ; Belongs to the class of potent (group III) corticosteroids, in combination with antibiotics. Used in the treatment of dermatological diseases.
Foskina B oint
5 g x 1's (P514.5/tube)
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