Folmaterna

Each capsule contains 5 mg Folic Acid.

Anti-anemia.
Pharmacology: Pharmacokinetics: Folic acid is rapidly absorbed from the gastrointestinal tract, mainly from the duodenum and jejunum. Dietary folates are stated to have about half the bioavailability of crystalline folic acid. The naturally occurring folate polyglutamates are largely deconjugated and reduced by dihydrofolate reductase in the intestines to form 5-methyltetrahydrofolate, which appears in the portal circulation, where it is extensively bound to plasma proteins. Folic acid administered therapeutically enters the portal circulation largely unchanged since it is a poor substrate for reduction by dihydrofolate reductase. It is converted to the metabolically active form 5-methyltetrahydrofolate in the plasma and liver.
The principal storage site of folate is the liver, it is also actively concentrated in the CSF.
Folate metabolites are eliminated in the urine and folate in excess of body requirements is excreted in unchanged in the urine. Folate is distributed into breast milk. Folic acid is removed by haemodialysis.

Folic acid is used in the treatment and prevention of the folate deficiency state. It is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring. For the treatment of folate deficient megaloblastic anaemia.

It is given by mouth in doses of 5 mg daily for 4 months; up to 15 mg daily may be necessary in malabsorption states. Continued administration of folic acid 5 mg every 1 to 7 days by mouth may be necessary in chronic haemolytic.
For child-bearing women, usual dose is 4 mg to 5 mg daily starting before pregnancy and continued through the first trimester.

Folic acid should never be given alone or in conjunction with inadequate amounts of Vit B₁₂ for the treatment of undiagnosed megaloblastic anaemia.

It is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring.

Folic acid metabolism may be affected by a number of drugs and anticonvulsants, oral contraceptives, antituberculosis drugs, alcohol, and folic acid antagonist including aminopterin, methotrexate, pyrimethamine, trimethoprim and sulfonamides which have said to produce folic acid deficiency states.

Store at temperatures not exceeding 30°C. Protect from light.

Vitamins & Minerals (Pre & Post Natal) / Antianemics

B03BB01 - folic acid ; Belongs to the class of folic acid and derivatives. Used in the treatment of anemia.

Rx