Treatment & prevention of folate deficiency state. Protection against neural tube defects in the offspring of pregnant & women of child-bearing potential.
Folate-deficient megaloblastic anemia 5 mg daily for 4 mth. Malabsorption states Up to 15 mg daily. Chronic haemolytic state Continue w/ 5 mg every 1-7 days. Prevention of neural tube defects in the offspring of pregnant & women w/ child-bearing potential 5 mg daily prior to pregnancy & continued through the 1st trimester.
Megaloblastic anemia secondary to vit B12 deficiency. May produce hematologic remission while neurologic damage progresses. Not to be given before a diagnosis has been fully established. Large & continuous doses may lower the blood conc of vit B12.
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