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Felodipine should not be given during pregnancy.
Felodipine, like other effective arteriolar dilators may in rare cases precipitate significant hypotension, which in susceptible individuals, may result in myocardial ischaemia.
Dosage of felodipine should be adjusted carefully in geriatric patients and in patients with impaired hepatic function; the usual initial dose is 2.5 mg daily in such patients.
Withdraw if ischaemic pain occurs or existing pain worsens shortly after initiating treatment or if cardiogenic shock develops.
Concomitant oral administration of felodipine with grapefruit juice usually should be avoided since it may cause an increase in felodipine plasma concentrations.
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