Eurolac Dosage/Direction for Use

The recommended oral dose of Ketorolac tablet is 10 mg every 4 to 6 hours for pain as required. Doses exceeding 40 mg per day are not recommended. For patients receiving Ketorolac ampoules, and who are converted to Ketorolac tablets, the total combined daily dose should not exceed 90 mg (60 mg for the elderly, renally-impaired patients and patients less than 50 kg) and the oral component should not exceed 40 mg on the day the change of formulation is made. Patients should be converted to oral treatment as soon as possible.
Special dosage instructions: Elderly patients: Ketorolac Tablets: A longer dosing interval, e.g. 6-8 hours, is advisable in the elderly. The lower end of the dosage range is recommended for patients over 65 years of age.
Children: Safety and efficacy yin children have not been established. Therefore, Ketorolac is contraindicated for use in children under 16 years of age.
Renal impairment: Since Ketorolac trometamol and its metabolites are excreted primarily by the kidney, Ketorolac is contraindicated in moderate to severe renal impairment (serum creatinine >160 μmol/L); patients with lesser renal impairment should receive a reduced dose (not exceeding 60 mg per day I.V. or I.M.) and their renal status should be closely monitored.
Combination treatment: Opioid analgesics (e.g. morphine, pethidine) may be used concomitantly and may be required for optimal analgesic effect in the early postoperative period when pain is most severe. Ketorolac trometamol does not interfere with opioid binding and does not exacerbate opioid-related respiratory depression or sedation. When used in association with Ketorolac ampoules, the daily dose of opioid is usually less than that normally required. However, opioid side effects should still be considered, especially in day-case surgery.