Treatment of a patient with toxic manifestations consists of ensuring adequate ventilation and arresting convulsions. Ventilation should be maintained with supplemental oxygen, by assisted or controlled respiration, if necessary. Assessment of circulation immediately should follow and support given when necessary. Convulsions may be aborted by administration of drugs such as succinylcholine, diazepam or thiopental. If ventricular fibrillation or cardiac arrest occurs, effective cardiovascular resuscitation must be instituted.