Ertax Dosage/Direction for Use

Posology: Treatment: Adults and adolescents (13 to 17 years of age): The dose of ERTAPENEM is 1 gram (g) given once a day by the intravenous route.
Infants and children (3 months to 12 years of age): The dose of ERTAPENEM is 15 mg/kg given twice daily (not to exceed 1 g/day) by the intravenous route.
Prevention: Adults: To prevent surgical site infections following elective colorectal surgery, the recommended dosage is 1 g administered as a single intravenous dose to be completed within 1 hour prior to the surgical incision.
Paediatric population: The safety and efficacy of ERTAPENEM in children below 3 months of age have not yet been established. No data are available.
Renal impairment: ERTAPENEM may be used for the treatment of infections in adult patients with mild to moderate renal impairment. In patients whose creatinine clearance is >30 mL/min/1.73 m2, no dosage adjustment is necessary. There are inadequate data on the safety and efficacy of ertapenem in patients with severe renal impairment to support a dose recommendation. Therefore, ertapenem should not be used in these patients. There are no data in children and adolescents with renal impairment.
Haemodialysis: There are inadequate data on the safety and efficacy of ertapenem in patients on haemodialysis to support a dose recommendation. Therefore, ertapenem should not be used in these patients.
Hepatic impairment: No dosage adjustment is recommended in patients with impaired hepatic function.
Elderly: The recommended dose of ERTAPENEM should be administered, except in cases of severe renal impairment.
Method of administration: Intravenous administration: ERTAPENEM should be infused over a period of 30 minutes.
The usual duration of therapy with ERTAPENEM is 3 to 14 days but may vary depending on the type and severity of infection and causative pathogen(s). When clinically indicated, a switch to an appropriate oral antibacterial agent may be implemented if clinical improvement has been observed.