Eposino Adverse Reactions

Common: A few may have headache, low fever and fatigue, muscle pain and arthralgia at the initial state of drug administration. But most of the adverse reactions may be relieved upon duration of treatment accordingly and there is no need to discontinue the use of Eposino. If the previously-mentioned symptoms still exist, discontinuance of the drug may be considered.
Allergic Reactions: Allergic reactions eg, skin rashes or urticaria, including allergic shock may occur rarely, therefore, it is advised that a small dosage of Eposino should be used as an initial dose as well as in the beginning of reuse of Eposino, make sure that there are no abnormal reactions that occur before the use of full dose as prescribed. If they do occur, Eposino should be stopped immediately and the proper treatment provided.
Cardiovascular System: Hypertension or other symptoms caused by the exacerbation of existing hypertension and hypertensive encephalopathy may occur eg, headache, disturbance of consciousness, convulsion and sometimes even encephalorrhagia. Therefore, blood pressure should be monitored periodically, dosage may be decreased or stopped and the depressor drug may also be adjusted.
Hematological System: The blood viscosity may increase as hematocrit rises. For some patients receiving hemodialysis, the heparin dosage should be increased whenever necessary to prevent artificial renal hemoagglutination. Accordingly, patients who tend to have hypotension or suffer from artriovenous fistulae occlusion, should use acetylsalicylic acid or aspirin to prevent the hemo-occlusion.
Liver: Hepatic function impairment may occur, GOP and GPT may sometimes rise.
Gastrointestinal System: Nausea, vomiting, anorexia and diarrhea may happen occasionally when Eposino is used.