Ascorbic acid should be given with care to patients with hyperoxaluria and glucose-6-phosphate dehydrogenase (G6PD) deficiency. Tolerance may be induced with prolonged use of high doses.
In case of acute overdoses of zinc sulfate, use of emetics or gastric lavage should be avoided for this is corrosive due to the formation of zinc chloride by stomach acid; treatment consists of administration of milk or alkali carbonates and activated charcoal. Routinely monitor zinc status in patients receiving long term TPN (Total Parenteral Nutrition). Prolonged administration of high doses of zinc supplements by mouth leads to copper deficiency with associated sideroblastic anemia and neutropenia. Zinc toxicity has occurred after the use contaminated water in haemodialysis solution. Using chelating such as sodium calcium edentate may reduce high serum zinc concentration.
Consult the Doctor: If the patient experienced any undesirable effect, talk to a doctor.
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