Edemann Drug Interactions

Furosemide may increase blood glucose in diabetes mellitus. Skin of some patients may be more sensitive to the effects of sunlight while taking furosemide.
Furosemide may increase the ototoxic potential of aminoglycoside antibiotics.
Furosemide should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with furosemide, as in rheumatic disease, may experience salicylate toxicity at lower doses because of competitive renal excretory sites.
Furosemide has a tendency to antagonize the skeletal muscle-relaxing effect of tubocurarine and may potentiate the action of succinylcholine. Lithium generally should not be given with diuretics because they reduce lithium's renal clearance and add a high risk of lithium toxicity.
Furosemide may decrease arterial responsiveness to norepinephrine.