Dynastat Description

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Full Prescribing Info

Description

Parecoxib sodium (hereafter referred to as parecoxib) is the prodrug for the pharmacologically active moiety, valdecoxib. Following injection, parecoxib (Dynastat) is rapidly and completely hydrolyzed enzymatically to valdecoxib.
Parecoxib (Dynastat) is chemically designated: N-[[4-(5-methyl-3-phenyl-4 isoxazolyl)phenyl]sulfonyl] propanamide, sodium salt.
C₁₉H₁₇N₂O₄SNa, M.W. = 392.41.
CAS registry no: 198470-85-8.
Parecoxib (Dynastat) is a white to off-white solid that is very soluble in water. The formulated drug product is soluble in normal (0.9%) saline at >50 mg/mL.
Parecoxib (Dynastat) 40 mg vial: Drug: Each vial contains Parecoxib (as sodium) 40 mg.Diluent: Each 2 mL ampoule contains Sodium Chloride 0.9%.
For reconstitution with 2 mL of solvent. After reconstitution, the final concentration of parecoxib (Dynastat) is 20 mg/mL.

parecoxib

Manufacturer:

Pharmacia and Upjohn

Distributor:

Pfizer