Dormicum Caution For Usage

Solution for injection: Special Instructions for Use, Handling and Disposal: Do not dilute Midazolam (Dormicum) ampoule solutions with 6% Dextran 70 in dextrose.
Do not mix Midazolam (Dormicum) ampoule solutions in alkaline injections. Midazolam precipitates in sodium bicarbonate.
The Midazolam (Dormicum) ampoule solution can be diluted with sodium chloride 0.9%, dextrose 5% and 10%, levulose 5%, Ringer's solution and Hartmann's solution in a mixing ratio of 15 mg midazolam per 100‑1000 mL infusion solution. These solutions remain physically and chemically stable for 24 hours at room temperature, or 3 days at 5°C.
To avoid potential incompatibility with other solutions, Midazolam (Dormicum) ampoule solution must not be mixed with other solutions except those mentioned previously.
From a microbiological point of view the product should be used immediately. If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 h at 2-8°C, unless dilution has taken place in controlled and validated aseptic conditions.
Midazolam (Dormicum) ampoules are for single use only. Discard any unused solution.
The solution should be visually inspected prior to use. Only clear solutions without particles should be used.
Rectal administration: Rectal administration of the ampoule solution is performed by means of a plastic applicator fixed on the end of the syringe. If the volume to be administered is too small, water may be added up to a total volume of 10 mL.