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Pharmacology: Diclofenac Diethylamine (Diclogen) is a multi-action topical gel for quick relief from pain, swelling & inflammation.
Pharmacokinetics: When Diclofenac Diethylamine (Diclogen) is applied locally, the active substance is absorbed through the skin. In healthy volunteers approximately 6% of the dose applied is absorbed when determined by urinary excretion of diclofenac and its hydroxylated metabolites. Findings in patients confirm that diclofenac penetrates inflamed areas following local application of Diclofenac Diethylamine (Diclogen).
Synovial fluid and tissue levels of diclofenac are higher than those detected in plasma.
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