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Dalamax

Dalamax

clindamycin

Manufacturer:

Interphil

Distributor:

MedChoice Women's Health
Concise Prescribing Info
Contents
Clindamycin HCl
Indications/Uses
Treatment of serious anaerobic infections due to Bacteroides fragilis, staphylococcal & streptococcal infections.
Dosage/Direction for Use
Adult 150-300 mg every 6 hr. Severe infections 300-450 mg every 6 hr. Childn 3-6 mg/kg body wt every 6 hr, <12 mth or weighing ≤10 kg 37.5 mg every 8 hr.
Administration
May be taken with or without food: Swallow whole w/ a full glass of water & in an upright position.
Contraindications
Hypersensitivity to clindamycin or lincomycin. Patients w/ GI disease especially w/ history of colitis; diarrhea.
Special Precautions
Discontinue use if diarrhea & colitis develops. Renal & hepatic impairment. Monitor blood counts, renal & liver function on prolonged treatment. Pregnancy & lactation. Childn. Elderly.
Adverse Reactions
Abdominal pain or cramps, nausea, vomiting, diarrhea & loose stools. Antibiotic-associated pseudomembranous colitis. Skin rashes & urticaria, SJS, anaphylaxis, transient leucopenia, leucopenia w/ agranulocytosis, eosinophilia, thrombocytopenia, erythema multiforme, exfoliative & vesiculobullous dermatitis, polyarthritis, abnormal LFT, overt jaundice, hepatic damage.
Drug Interactions
Increased risk of resp depression w/ tubocurarine, pancuronium & atracurium. Delayed excretion of toxin w/ diphenoxylate, loperamide & other opiate antidiarrheal drugs. Reduced absorption w/ kaolin-pectin susp. Inhibited in vitro activity of aminoglycosides. Antagonized activity of parasympathomimetics eg, neostigmine & pyridostigmine.
MIMS Class
Other Antibiotics
ATC Classification
J01FF01 - clindamycin ; Belongs to the class of lincosamides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Dalamax cap 300 mg
Packing/Price
100's (P4,250/box, P42.5/cap)
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