D-Cure Dosage/Direction for Use

Paediatric posology: Prevention of deficiency 0-1 years 25000 IU (1 ampoule) every 8 weeks.
Prevention of deficiency 1-18 years 25000 IU (1 ampoule) every 6 weeks.
Treatment of deficiency 0-18 years 25000 IU (1 ampoule) once every 2 weeks for 6 weeks (followed by maintenance therapy of 400-1000 IU/day).
Pregnancy and breastfeeding: The high strength formulation is not recommended.
Adults: Prevention of vitamin D deficiency 25000 IU/month (1 ampoule), higher doses may be required in certain situations, see as follows.
As an adjunct to specific therapy for osteoporosis: 25000 IU/month (1 ampoule).
Treatment of vitamin D deficiency (<25 ng/ml) 50000 IU/week (2 ampoules) for 6-8 weeks, followed by maintenance therapy (1400-2000 IU/day may be required; follow-up 25(OH)D measurements should be made approximately three to four months after initiating maintenance therapy to confirm that the target level has been achieved).
Certain populations are at high risk of vitamin D deficiency, and may require higher doses and monitoring of serum 25(OH)D: Institutionalised or hospitalised individuals.
Dark skinned individuals.
Individuals with limited effective sun exposure due to protective clothing or consistent use of sunscreens.
Obese individuals.
Patients being evaluated for osteoporosis.
Use of certain concomitant medications (e.g., anticonvulsant medications, glucocorticoids).
Patients with malabsorption, including inflammatory bowel disease and coeliac disease.
Those recently treated for vitamin D deficiency, and requiring maintenance therapy.
Special populations: Renal impairment: Cholecalciferol (D-Cure) should not be used in combination with calcium in patients with severe renal impairment.
Hepatic impairment: No posology adjustment is required in patients with hepatic impairment.
Method of Administration: Patients should be advised to take Cholecalciferol (D-Cure) preferably with meal.
Administration to adults: The full contents of the ampoule should be either emptied into the mouth and swallowed orally, or emptied onto a spoon and taken orally. Cholecalciferol (D-Cure) can also be taken by mixing with a small amount of cold or lukewarm food immediately prior to use.
Administration to children: In children, Cholecalciferol (D-Cure) can be mixed with a small amount of children's foods, yogurt, milk, cheese or other dairy products. The parents should be warned not to mix Cholecalciferol (D-Cure) into a bottle of milk or container of soft foods in case the child does not consume the whole portion, and does not receive the full dose. The parents should ensure that their child takes the entire dose. For children who are not breast-feeding, the prescribed dose should be administered with a meal