Treatment of pancreatic exocrine insufficiency in pediatric and adult patients often associated with, but not limited to: Cystic fibrosis; chronic pancreatitis; pancreatic surgery; gastrectomy; pancreatic cancer; gastrointestinal bypass surgery (e.g. Billroth II gastroenterostomy); ductal obstruction of the pancreas or common bile duct (e.g. from neoplasm); Shwachman-Diamond Syndrome; status after an attack of acute pancreatitis and initiation of enteral or oral feeding.