Advertisement
Advertisement
Cozaar XQ

Cozaar XQ Description

amlodipine + losartan

Manufacturer:

Hanmi Pharmaceutical

Distributor:

Organon
Full Prescribing Info
Description
LOSARTAN POTASSIUM + AMLODIPINE CAMSYLATE (COZAAR XQ) is containing 50 mg of losartan potassium and 7.84 mg of amlodipine camsylate (equivalent to 5 mg amlodipine).
LOSARTAN POTASSIUM + AMLODIPINE CAMSYLATE (COZAAR XQ) is containing 100 mg of losartan potassium and 7.84 mg of amlodipine camsylate (equivalent to 5 mg amlodipine).
LOSARTAN POTASSIUM + AMLODIPINE CAMSYLATE (COZAAR XQ) is a combination of an angiotensin II receptor (type AT1) antagonist and a calcium channel blocker.
LOSARTAN POTASSIUM + AMLODIPINE CAMSYLATE (COZAAR XQ) contains losartan potassium and amlodipine camsylate.
Losartan potassium: Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol monopotassium salt.
Its empirical formula is C22H22ClKN6O.
Losartan potassium is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone.
Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.
Amlodipine camsylate: Amlodipine camsylate is chemically described as 3-ethyl 5-methyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate camphor sulfonate.
Its empirical formula is C20H25ClN2O5·C10H16O4S.
Amlodipine camsylate is a white to slightly yellow crystalline powder with a molecular weight of 641.17. It is freely soluble in chloroform, dimethylformamide and dimethyl sulfoxide and slightly soluble in water, ethanol and methylene chloride.
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement