Epilepsy 150 mg daily in 2 or 3 divided doses, increased after 1 wk according to response to 300 mg daily & then to 600 mg daily after another wk. Generalized anxiety disorder Initially 150 mg daily in 2 or 3 divided doses, may be increased at wkly intervals in steps of 150 mg, to max of 600 mg daily. Neuropathic pain Initially 150 mg daily in 2 or 3 divided doses, increased after 3-7 days to 300 mg daily & then to 600 mg daily after another 7 days. Max daily dose of 300 mg is recommended in diabetic neuropathy. Fibromyalgia Initially 150 mg daily in 2 or 3 divided doses, increased after 1 wk according to response to 300 mg daily & then to 450 mg daily if necessary
Gradual w/drawal of therapy in epilepsy or transitioning to or from another type of antiepileptic therapy to avoid precipitating increase in seizure frequency.
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