Comfora Dosage/Direction for Use

Adults: The recommended dose of pentosan polysulfate sodium is 300 mg/day taken as one 100 mg capsule orally three times daily.
Response to treatment with pentosan polysulfate sodium should be reassessed every 3 months. In case no improvement is reached 6 months after treatment initiation, treatment with pentosan polysulfate sodium should be stopped. In responders, pentosan polysulfate sodium treatment should be continued chronically as long as the response is maintained.
Special populations: Pentosan polysulfate sodium has not been specifically studied in special patient populations like elderly, male patients or patients with renal or hepatic impairment. No dose adjustment is recommended for these patients.
Pediatric population: The safety and efficacy of pentosan polysulfate sodium in children and adolescent below 18 years has not been established. No data are available.
Method of administration: The capsules should be taken with water at least 1 hour before meals or 2 hours after meals.
Or as prescribed by the physician.