Clovate Use In Pregnancy & Lactation

Pregnancy: Cream: There are limited data from the use of clobetasol in pregnant women.
Topical administration of corticosteroids to pregnant animals can cause abnormalities of foetal development.
The relevance of this finding to humans has not been established. Administration of clobetasol during pregnancy should only be considered if the expected benefit to the mother outweighs the risk to the fetus. The minimum quantity should be used for the minimum duration.
Ointment: Clobetasol propionate ointment should not be used in pregnant women unless the potential benefit justifies the potential risk to the fetus.
Lactation: Cream: The safe use of topical corticosteroids during lactation has not been established.
It is not known whether the topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable amounts in breast milk. Administration of clobetasol during lactation should only be considered if the expected benefit to the mother outweighs the risk to the infant.
If used during lactation clobetasol should not be applied to the breasts to avoid accidental ingestion by the infant.
Ointment: It is not known whether topically applied Clobetasol propionate is secreted in breast milk. Caution should be exercised when Clobetasol propionate ointment is prescribed to nursing women.
Fertility: Cream: There are no data in humans to evaluate the effect of topical corticosteroids on fertility.
Clobetasol administered subcutaneously to rats had no effect upon mating performance; however, fertility was decreased at the highest dose.