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Gastro-intestinal tract: Nausea, vomiting, abdominal pain and diarrhea.
Haematopoietic: Transient neutropenia (leucopenia), eosinophilia, agranulocytosis and thrombocytopenia have been reported.
No direct aetiologic relationship to concurrent clindamycin therapy could be made in any of the foregoing.
Skin and mucous membranes: Pruritus, vaginitis and rare instances of exfoliative and vesiculobullous dermatitis have been reported.
Hypersensitivity reactions: Maculopapular rash and urticaria have been observed during drug therapy. Generalized mild to moderate morbilliform-like skin rashes are the most frequent reported reactions.
Rare instances of erythema multiforme, some resembling Stevens-Johnson syndrome, have been associated with clindamycin. A few cases of anaphylactoid reactions have been reported.
Liver: Jaundice and abnormalities in liver function tests have been observed during clindamycin therapy.
