Clindagen Dosage/Direction for Use

The usual oral dose of clindamycin in adults is 150 to 300 mg every 6 hours. For very severe infections, dose is increased to 300-450 mg every 6 hours. Children may be given 3-6 mg per kg body weight every 6 hours. Children below 12 months or weighing ≤10 kg are given 37.5 mg every 8 hours.
Or as prescribed by the physician.
It is recommended that clindamycin capsule should be taken with a full glass of water to avoid esophageal irritation.
Dose must be reduced if clindamycin is to be given to patients with hepatic failure.
Prior to surgeries or procedures such as dental extractions with local or no anesthesia. patients who have a high risk of endocarditis where penicillin is inappropriate should be given clindamycin 600 mg orally one hour before the procedure. Patients who will undergo procedures with general anesthesia and cannot be given penicillin require administration of injectable 300 mg clindamycin 10-15 minutes before the procedure followed by oral or intravenous clindamycin 150 mg after 6 hours.