FC tabAdult 250 mg bid, may be increased to 500 mg bid in severe infection. Childn 15 mg/kg daily in 2 divided doses. Max: 500 mg every 12 hr. Duration: 5-14 days (6-14 days for community-acquired pneumonia & sinusitis). Granules for suspChildn 15 mg/kg daily in 2 divided doses. Max: 500 mg every 12 hr. Duration: 5-14 days (6-14 days for community-acquired pneumonia & sinusitis). Childn 7-12 yr 7.5-10 mL every 12 hr, 2-6 yr 5 mL every 12 hr, 6 mth-1 yr 2.5 mL every 12 hr.
View Claryn overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Granules for susp: Add approx 40 mL water to make 50 mL reconstituted susp. Shake well until granules are evenly suspended.
Contraindications
Hypersensitivity to clarithromycin, erythromycin, or any macrolides. Granules for susp: Patients w/ history of cholestatic jaundice/hepatic dysfunction associated w/ prior use of clarithromycin. Concomitant administration w/ cisapride, pimozide, astemizole, terfenadine, & ergotamine or dihydroergotamine. Co-administration w/ colchicine in patients w/ renal or hepatic impairment.
Patients w/ renal or hepatic impairment. Reduce dose in patients w/ severe renal impairment. Pregnancy. Granules for susp: Discontinue use in case of signs & symptoms of hepatitis; suspected or confirmed Clostridium difficile-associated diarrhea. Safety has not been established during breast-feeding of infants.
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