Indicated for the treatment of the following infections. Special attention should be paid to available information on resistance to ciprofloxacin before commencing therapy.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Adults: Lower respiratory tract infections due to gram-negative bacteria: exacerbations of chronic obstructive pulmonary disease; broncho-pulmonary infections in cystic fibrosis or in bronchiectasis; pneumonia.
Chronic suppurative otitis media; Acute exacerbation of chronic sinusitis especially if these are caused by gram-negative bacteria; Urinary tract infections; Genital tract infections.
Gonococcal urethritis and cervicitis due to susceptible Neisseria gonorrhoeae.
Epididymo-orchitis including cases due to susceptible Neisseria gonorrhoeae.
Pelvic inflammatory disease including cases due to susceptible Neisseria gonorrhoeae.
In the previously mentioned genital tract infections when thought or known to be due to Neisseria gonorrhoeae, it is particularly important to obtain local information on the prevalence of resistance to ciprofloxacin and to confirm susceptibility based on laboratory testing.
Infections of the gastro-intestinal tract (e.g. travelers' diarrhoea).
Intra-abdominal infections.
Infections of the skin and soft tissue caused by gram-negative bacteria; Malignant external otitis; Infections of the bones and joints.
Treatment of infections in neutropenic patients.
Prophylaxis of infections in neutropenic patients.
Prophylaxis of invasive infections due to Neisseria meningitides.
Inhalation anthrax (post-exposure prophylaxis and curative treatment).
Ciprofloxacin may be used in the management of neutropenic patients with fever that is suspected to be due to a bacterial infection.
Paediatric population: Broncho-pulmonary infections in cystic fibrosis caused by Pseudomonas aeruginosa.
Complicated urinary tract infections and pyelonephritis.
Inhalation anthrax (post-exposure prophylaxis and curative treatment).
Ciprofloxacin may also be used to treat severe infections in children and adolescents when this is considered to be necessary.
Treatment should be initiated only by physicians who are experienced in the treatment of cystic fibrosis and/or severe infections in children and adolescents.
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