Ciprobay Caution For Usage

Instructions for use/ handling: Ciprofloxacin (Ciprobay) solution for infusion: At cool storage temperatures precipitation may occur, which will re-dissolve at room temperature. It is therefore recommended not to store the infusion solution in a refrigerator.
Incompatibilities: Film-coated tablet: None.
Solution for infusion: Ciprofloxacin (Ciprobay) solution for infusion (0.9% NaCl): Ciprofloxacin (Ciprobay) solution for infusion (0.9% NaCl) is compatible with physiological saline, Ringer solution and Ringer lactate solution, 5% and 10% glucose solutions, 10% fructose solution, and 5% glucose solution with 0.225% NaCl or 0.45% NaCl.
When Ciprofloxacin (Ciprobay) solutions for infusion (0.9% NaCl) are mixed with compatible solutions for infusion, for microbiological reasons and light sensitivity, these solutions should be administered shortly after admixture. Unless compatibility with other solutions for infusion/medicinal products has been confirmed, the solution for infusion must always be administered separately. The visual signs of incompatibility are e.g. precipitation, clouding, and discoloration.
Incompatibility appears with all solutions for infusion/medicinal products that are physically or chemically unstable at the pH of the solution (e.g. penicillins, heparin solutions), especially on combination with solutions adjusted to an alkaline pH (pH of the Ciprofloxacin (Ciprobay) solutions for infusion (0.9% NaCl: 3.9 - 4.5).