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Cefazolin is indicated in the treatment of the following infections when due to susceptible micro-organisms: Respiratory tract infections due to S. pneumoniae, Klebsiella sp., S. influenzae, S. aureus (including penicillinase-producing strains), and group A B-hemolytic streptococci.
Genitourinary tract infections due to E. coli, P. mirabilis, Klebsiella sp., and some strains of Enterobacter and enterococci.
Skin and skin structure infections due to S. aureus (including penicillinase-producing strains) and group A B-hemolytic streptococci and other strains of streptococci.
Biliary tract infections due to Escherichia coli, various strains of streptococci, Proteus mirabilis, Klebsiella species and Staphylococcus aureus.
Bone and joint infections due to S. aureus, Septicemia due to S. pneumoniae, S. aureus (penicillin susceptible and penicillin-resistant).
Endocarditis due to S. aureus (penicillin-susceptible and penicillin-resistant) and group A B-hemolytic streptococci.
Perioperative prophylaxis.
