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Pregnancy: Pregnancy Category C. Beta-blockers decrease placental perfusion, which may result in intrauterine fetal death, and immature and premature deliveries. Also, adverse effects (particularly hypoglycemia and bradycardia) may occur in the fetus and neonate. An increased risk of cardiac and pulmonary complications in the neonate in the postnatal period may be observed. There are no adequate and controlled studies to date using carvedilol in pregnant women. Carvedilol should be used in pregnancy only when the potential benefits justify the potential risks to the fetus.
Lactation: In animal studies, carvedilol and its metabolites are excreted in breast milk. It is not known whether carvedilol is excreted in human milk. Thus, breastfeeding is not recommended during carvedilol administration.
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