As a substitute for oral nicardipine therapy 0.5 mg/hr IV infusion rate (for oral 20 mg every 8 hr), 1.2 mg/hr IV infusion rate (for oral 30 mg every 8 hr), 2.2 mg/hr IV infusion rate (for oral 40 mg every 8 hr). Initiation of therapy in drug-free patient 0.1 mg/mL administered by slow continuous infusion. Gradual reduction in BP Initially 5 mg/hr, may be increased by 2.5 mg/hr every 15 min up to a max of 15 mg/hr. More rapid BP reduction Initially 5 mg/hr, may be increased by 2.5 mg/hr every 5 min up to a max of 15 mg/hr. Decrease to 3 mg/hr following achievement of bp goal.
C08CA04 - nicardipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
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