Capmerin Adverse Reactions

Concise Prescribing Info Full Prescribing Info Contents Description Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Full Prescribing Info

Adverse Reactions

The main adverse effect of treatment with Mercaptopurine is bone marrow depression leading to leukopenia and thrombocytopenia. Mercaptopurine is hepatotoxic in animals and man. The incidence of hepatotoxicity can occur with any dose but more frequently when the recommended dose of 2.5 mg/kg bodyweight daily is exceeded.
The histological findings in man have shown hepatic necrosis and biliary stasis.
Anorexia, nausea, vomiting and oral ulceration may occasionally occur, and intestinal ulceration has rarely been reported.
Rare complications are drug fever and skin rash.

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mercaptopurine

Manufacturer:

Korea United Pharma

Distributor:

Qualimed