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Combination therapy with bicalutamide 50 mg: Adult males including the elderly: One tablet (50 mg) once daily with or without food.
Treatment with bicalutamide may be started either 3 days before or at the same time as commencing treatment with an LHRH analogue, or at the same time as surgical castration.
Monotherapy with 3 tablets of bicalutamide 50 mg (150 mg bicalutamide): Adult males including the elderly: Three tablets (150 mg) once daily with or without food.
Bicalutamide 150 mg should be taken continuously for at least 2 years or until disease progression.
Renal impairment: No dosage adjustment is necessary for patients with renal impairment.
Hepatic impairment: No dosage adjustment is necessary for patients with mild hepatic impairment. Increased accumulation may occur in patients with moderate to severe hepatic impairment.
