Buscopan Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Hyoscine-N-butylbromide

Indications/Uses

Acute GIT spasm, GUT spasm, biliary system spasm. Inj: Aid in diagnostic & therapeutic procedures eg, gastroduodenal endoscopy, radiology.

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Dosage/Direction for Use

Tab Adult & childn >6 yr 1-2 tab 3-5 times daily. Inj Adult & adolescent >12 yr 20-40 mg by slow IV, IM or SC several times daily. Max: 100 mg daily. Infant & childn Severe cases: 0.3-0.6 mg/kg by slow IV, IM or SC several times daily. Max: 1.5 mg/kg daily.

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Overdosage

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Administration

May be taken with or without food: Swallow whole w/ adequate fluid.

Contraindications

Hypersensitivity. Myasthenia gravis, mechanical stenosis in GIT, paralytical or obstructive ileus, megacolon, narrow-angle glaucoma, prostate hypertrophy w/ urinary retention, tachycardia. Tab: Hereditary conditions of fructose intolerance. Inj: IM inj in patients on anticoagulants.

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Special Precautions

Seek medical advice in case of persisting or worsening severe, unexplained abdominal pain w/ symptoms eg, fever, nausea, vomiting, changes in bowel movement, abdominal tenderness, decreased BP, fainting or blood in stool. Patients w/ undiagnosed & untreated narrow-angle glaucoma. Pregnancy & lactation. Patients susceptible to intestinal or urinary outlet obstructions, inclined to tachyarrhythmia. Due to possible visual accommodation disturbances, avoid driving or operating machinery. Tab: Conditions characterised by tachycardia eg, thyrotoxicosis, cardiac insufficiency or failure & in cardiac surgery. Inj: Anaphylaxis. Monitor patients w/ cardiac conditions submitted to parenteral treatment.

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Use In Pregnancy & Lactation

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Adverse Reactions

Anaphylactic reactions & shock, dyspnoea, skin reactions (eg, urticaria, rash, erythema, pruritus) & other hypersensitivity; tachycardia; GI disorders, dry mouth; dyshidrosis; urinary retention. Tab: Abnormal sweating. Inj: Visual accommodation disorders, mydriasis, increased IOP; decreased BP, dizziness, flushing.

Drug Interactions

Intensified anticholinergic effects of tri- & tetracyclic antidepressants, antihistamines, antipsychotics, quinidine, amantadine, disopyramide & other anticholinergics (eg, tiotropium, ipratropium, atropine-like compd). Diminution of the effects of both drugs on GIT w/ dopamine antagonists eg, metoclopramide. Enhanced tachycardic effects of β-adrenergic agents.

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Storage

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Description

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Action

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MIMS Class

Antispasmodics

ATC Classification

A03BB01 - butylscopolamine ; Belongs to the class of belladonna alkaloids, semisynthetic, quaternary ammonium compounds. Used in the treatment of functional gastrointestinal disorders.

Regulatory Classification

Tab: Non-Rx; Inj: Rx

Presentation/Packing

Form

Buscopan inj 20 mg

Packing/Price

(amp) 10 × 1's (P1,677.5/box)

Form

Buscopan sugar-coated tab 10 mg

Packing/Price

120's (P3,150/pack);4's (P97/pack)

Buscopan

hyoscine

Manufacturer:

Opella Healthcare

Distributor:

Opella Healthcare