Amoxicillin is comparatively safer and better tolerated since the hepatic, renal and hematopoietic side-effects seen in other broad-spectrum antibiotics are rare. As with other penicillins, it may be expected that untoward reactions are related sensitivity phenomena which include skin rashes and urticaria. Gastrointestinal manifestations may be experienced such as diarrhea, indigestion, glossitis, stomatitis and vomiting.