Should be taken on an empty stomach: Take 1 hr before or 2 hr after intake of food or fruit juice. Place in the mouth to rapidly disperse then swallow. May also disperse tab in water. Do not use grapefruit juice or any other fruit juices for dispersion.
Avoid coadministration w/ P-gp inhibitors eg, ketoconazole, erythromycin, cyclosporine, ritonavir or diltiazem in patients w/ moderate or severe renal impairment. May affect the ability to drive or use machines. Avoid use during pregnancy. Lactation. Childn <6 yr & <20 kg.