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Pharmacology: Pharmacodynamics: POVIDONE-IODINE (BETADINE) is a topical agent active against organisms commonly encountered in skin and wound infections. It contains 10% povidone-iodine equivalent to 1% available iodine.
The active ingredient, povidone-iodine, substantially retains the broad spectrum germicidal activity of iodine against the commonly encountered organisms in skin and wound infections, without the undesirable features or disadvantages of iodine.
POVIDONE-IODINE (BETADINE) is decisively microbicidal against all 4 major classes of pathogens: bacteria (both Gram-positive and Gram-negative, as well as antibiotic-resistant strains) fungi, viruses and protozoa. The foremost documented broad spectrum topical microbicidal power of POVIDONE-IODINE (BETADINE) is active even in the presence of blood, pus and serum and the germicidal activity is more prolonged than that of iodine tincture.
POVIDONE-IODINE (BETADINE) is in a water-soluble base and is not greasy or sticky. It permits bandaging of treated area, is virtually non-irritating to skin and mucosa and does not block air from reaching site of application. It easily washes off from skin and natural fabrics.
Ointment: POVIDONE-IODINE (BETADINE) ointment does not interfere with granulation or skin grafting in burns.
