It is used to reduce LDL-cholesterol, Apolipoprotein B, and triglycerides, and to increase HDL-cholesterol in the treatment of hyperlipidaemias, including hypercholesterolaemias and combined (mixed) hyperlipidaemia (Type IIa or IIb hyperlipoproteinaemias), hypertriglyceridaemia (Type IV), and dysbetalipoproteinaemia (Type III) and also can be effective as adjunct therapy in patients with homozygous familial hyper-cholesterolaemia who have some LDL-receptor function.