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Fosphenytoin sodium (Aurantin) is contraindicated in patients who are hypersensitive to fosphenytoin or its inactive ingredients or to phenytoin or other hydantoins.
Because of the effect of phenytoin on ventricular automaticity, fosphenytoin sodium (Aurantin) is contraindicated in patients with sinus bradycardia, sinoatrial block, second and third-degree atrioventricular (AV) block, and Adams-Stokes syndrome.
Co-administration of fosphenytoin sodium (Aurantin) is contraindicated with delavirdine due to the potential for loss of virologic response and possible resistance to delavirdine or to the class of non-nucleoside reverse transcriptase inhibitors.
